Specifications
Brand Name :
HJW
Certification :
ISO 14001,ISO 9001,CE,EPA
Place of Origin :
Shenzhen,Guangdong
MOQ :
1set
Price :
negotiation
Payment Terms :
L/C,D/P,T/T,Western Union
Supply Ability :
>300sets/month
Delivery Time :
1-7working days(depand on raw materials stocking)
Packaging Details :
export standard wooden case
Capacity :
500L/H(Customizable)
Core Process :
UF
Core Components :
Pump, Motor, PLC
Material :
FRP,Stainless steel
Recovery Rate :
> 95%
Membrane Module Type :
Hollow Fiber,Flat Sheet Membrane Pack,Ceramic Membrane
Description

I.Overview
Ultrafiltration (UF) assumes the core tasks of concentration, purification, buffer replacement and removal of impurities in the separation of biological products, and is especially suitable for the fine treatment of large molecules of biologically active substances (e.g. proteins, vaccines, nucleic acids). UF system is the gold standard of biologics separation, and its irreplaceable core value in biopharmaceuticals lies in: activity preservation, precise separation, and compliance guarantee.


II.Key technology flow
Typical route for downstream purification of monoclonal antibody:
cell culture solution → centrifugation/microfiltration → Protein A chromatography → virus inactivation → **UF/DF (ultrafiltration dialysis)** → purified chromatography → preparation


Plasmid DNA purification process:
bacteriophage lysis → alkaline extraction → ultrafiltration (100 kDa) → affinity chromatography → **tangential flow ultrafiltration (TFF)** → sterile filtration


III.Core Performance Parameters

Parameter Standard Requirement
Molecular Weight Cut - off 1/3 - 1/6 of the target molecular weight (e.g., 30 kDa for monoclonal antibodies)
Recovery Rate > 95% (for monoclonal antibodies)
HCP Residue < 100 ppm
Endotoxin Removal < 0.001 EU/mg
Shear Force Control Laminar shear force < 10 Pa·s


IV.Key Points for Equipment Selection

Membrane Module Type Applicable Scenarios
Hollow Fiber Large - volume Processing (>500L)
Flat Sheet Membrane Pack High - value - added Products (e.g., Gene Therapy)
Ceramic Membrane High - Viscosity/Particulate - containing Feed Liquid


V.Core Application Scenarios
Monoclonal Antibodies
Recombinant Proteins
Viral Vectors
Nucleic Acid Drugs
Vaccines


VI.Here is a guideline for you to get a proper quotation
Tell us the raw water/source of water(tap water, well water, or sea water, etc)
Provide water analysis report(TDS , conductivity, or resistivity, etc)
Required production capacity( 5m³/H, 50m³/H,or 500m³/H, etc)
What's the pure water used for( industrial,Food and Beverage,or agriculture, etc )


Send your message to this supplier
Send Now

Factory Price Ultrafiltration unit for Separation of biological products 500 lters per hour water filtration system

Ask Latest Price
Brand Name :
HJW
Certification :
ISO 14001,ISO 9001,CE,EPA
Place of Origin :
Shenzhen,Guangdong
MOQ :
1set
Price :
negotiation
Payment Terms :
L/C,D/P,T/T,Western Union
Contact Supplier
Factory Price  Ultrafiltration unit for Separation of biological products 500 lters per hour  water filtration system

Shenzhen HongJie Water Technology Co., Ltd.

Verified Supplier
1 Years
shenzhen
Since 2013
Business Type :
Manufacturer
Total Annual :
25000000-30000000
Employee Number :
180~200
Certification Level :
Verified Supplier
Contact Supplier
Submit Requirement