Cynarin, also known as cynarinic acid and cynaroic acid, is an organic compound with the CAS number 30964-13-7 and the molecular formula C₂₅H₂₄O₁₂. It occurs naturally in the Asteraceae plants artichoke, the whole herb of Senecio sylvatica, and honeysuckle, and can also be obtained through chemical synthesis or plant extraction. It is a white crystalline powder with a melting point of 225-227°C. It is relatively soluble in boiling water, ethanol, and glacial acetic acid, and slightly soluble in cold water.
Cynarin has choleretic, hepatoprotective, and cholesterol-lowering properties and is clinically used to treat diseases associated with liver dysfunction. It also exerts neuroprotective effects by activating the PI3K/Akt pathway. Its antioxidant activity is stronger than ascorbic acid and can inhibit hepatitis B virus and HIV. Related research has entered the clinical trial stage. The preparation method, which includes alkaline solution treatment and ethanol crystallization, can improve yield and reduce costs.
Items | Standards | Results |
Physical Analysis | ||
Appearance | Fine Powder | Conforms |
Color | Brown Powder | Conforms |
Odor | Characteristic | Conforms |
Mesh Size | 100% through 80% mesh size | Conforms |
General Analysis | ||
Identification | Identical to R.S. sample | Conforms |
Cynarin | ≥5% | 5.41% |
Extract Solvents | Water and Ethanol | Conforms |
Loss on Drying (g/100g) | ≤5.0 | 3.24% |
Ash(g/100g) | ≤5.0 | 2.05% |
Chemical Analysis | ||
Pesticides Residue (mg/kg) | 0.05 | Conforms |
Residual Solvent | <0.05% | Conforms |
Residual Radiation | Negative | Conforms |
Lead(Pb) (mg/kg) | <3.0 | Conforms |
Arsenic(As) (mg/kg) | <2.0 | Conforms |
Cadmium(Cd) (mg/kg) | <1.0 | Conforms |
Mercury(Hg) (mg/kg) | <0.1 | Conforms |
Microbiological Analysis | ||
Total Plate Count(cfu/g) | ≤1,000 | 300 |
Molds and Yeast (cfu/g) | ≤100 | 29 |
Coliforms (cfu/g) | Negative | Conforms |
Salmonella(/25g) | Negative | Conforms |
Our packing method is 1KG/Aluminium bags, 25kg/drum
For some products that require special packaging during transportation, we will carry out more delicate packaging. For example, retinal needs to be stored at -20 °C, so we choose cold chain transportation during transportation; deoxyarbutin will change color during transportation, so we will Vacuum packing of deoxyarbutin