Sterile Liquid Filling Machine for 30–500 ml Glass & Plastic Bottles with Nitrogen Protection

Core System Features

• Integrated Nitrogen Protection: Configurable with nitrogen flushing and padding capabilities (applied before and/or after filling). This drastically reduces headspace oxygen, making it highly suitable for aseptic or quasi-aseptic processes and oxidation-sensitive active ingredients.

• Versatile Dispensing Technologies: Supports multiple filling mechanisms within a single platform, including normal pressure, vacuum, and peristaltic or stainless steel piston pumps. This flexibility ensures stable processing for both low-viscosity fluids and higher-viscosity emulsions.

• High-Yield & Low-Loss Operation: Engineered for precision and material conservation, achieving a volumetric filling accuracy of ± 1%, a capping success rate exceeding 99%, and a strictly controlled bottle breakage rate of under 0.5%.

• Intelligent PLC Control System: Governed by a A sterile Logic Controller (PLC) with an intuitive touchscreen HMI. The system enables real-time monitoring of filling speeds, volumes, and diagnostics, while generating electronic production and batch records.

• Rapid Modular Changeover: Features a quick-release structural design allowing operators to transition between different bottle dimensions or liquid formulations in under 30 minutes, significantly improving Overall Equipment Effectiveness (OEE).

Typical Application Range

• Steriles & Healthcare: Oral liquids, syrups, pediatric formulations, medical disinfectants, and antiseptic solutions.

• Cosmetics & Personal Care: High-value serums, essences, toners, lotions, and fluid emulsions.

• Household & Chemical: Liquid soaps, hand sanitizers, glass cleaners, and multi-purpose cleaning agents.

Technical Specifications

Regulatory Compliance & Validation Support

Our equipment is engineered to meet strict international regulatory standards, ensuring seamless integration into your facility's quality management systems.

• Complete Validation Documentation (DQ/IQ/OQ/PQ): We provide comprehensive validation protocols to support your regulatory submissions, including Design, Installation, Operational, and Performance Qualifications, alongside complete material traceability certificates for all product-contact components (including FDA food-grade certified materials).

• GMP & ISO 13485 Compliant Sanitary Design: Built strictly to Good Manufacturing Practice (GMP) and ISO 13485 principles. The equipment features crevice-free stainless steel construction and sanitary piping, and is fully compatible with CIP/SIP (Clean-in-Place / Sterilize-in-Place) procedures to eliminate contamination risks.

• Data Integrity & Traceability: Designed to support FDA 21 CFR Part 11 requirements. Our intelligent PLC systems feature secure multi-level user access, automated electronic audit trails, and real-time batch data recording that can be easily exported or integrated into your SCADA/MES systems.