Pharmaceutical Vial Filling Machine For Recombinant Humanized Collagen Solutions, Precision Aseptic Processing With Nitrogen Filling Protection Equipment

Engineered for High-Value Biopharmaceuticals: Stability Meets Scalability

Key Differentiators vs Competitors

✅ Collagen-Specific Sterilization Protocol

• Patented dry-heat sterilization tunnel (up to 320°C) reduces endotoxins by 3-log reduction, critical for preserving bioactivity in recombinant collagen solutions .
• Nitrogen-shielded filling prevents oxidation of pH-sensitive formulations.

✅ Adaptive Modular Design

• Seamlessly switches between 2-30ml vial formats (including RUP* vials for clinical trials) without tooling changes.
• AI-powered vision system detects micro-cracks in glass vials (accuracy: 99.98%) to avoid protein degradation risks.

✅ End-to-End Traceability

• Integrated FDA 21 CFR Part 11-compliant data logging tracks batch parameters (temperature, fill weight, stopper insertion depth) for biologics compliance .

Technical Parameters

Target Applications

• Regenerative Cosmeceuticals: Fill-sterilize recombinant collagen for dermal fillers and wound healing gels.
• Ophthalmic Biologics: Precision filling of collagen-based corneal repair solutions.
• 3D Bioprinting Precursors: Aseptic preparation of bioink containing humanized collagen matrices.

Why Suzhou Lingyao Stands Out?

• Proprietary "Cold Necking" Technology: Minimizes thermal stress on vial necks during sealing – reduces breakage by 40% vs conventional methods .
• Dual Certification Advantage: Simultaneously complies with China NMPA and EU GMP Annex 1 standards for global market access.
• On-Demand Scalability: Upgradeable to lyophilization-ready configurations for collagen-based freeze-dried powders.