Peptide synthesis protectant Chemical Auxiliary Agent Triisopropylsilane CAS 6485-79-6
Introduction:
Colorless liquid, B.P.84-85℃(35mmHg), F.P.35℃,d 0.773.nD201.4340. This product is flammable and irritating
Uses:
Protecting agent for peptide synthesis. The bulky isopropyl group (compared to the ethyl group) enables more selective reduction reactions (e.g., β-selective reduction of anomeric C-phenyl ketals) without reducing their activity (e.g., trifluoromethanesulfonate-catalyzed reductive etherification of trimethylsilyl). Used in the highly diastereoselective preparation of trans-1,2-diols catalyzed by Ni(O)N-heterocyclic carbene complexes.
Product Name | Triisopropylsilane |
CAS | 6485-79-6 |
MF | C9H22Si |
MW | 158.36 |
EINECS | 464-880-1 |
Color | colorless liquid |