Buserelin Acetate Peptide Powder (CAS 57982-77-1)
Buserelin (also known as Buserelin Acetate) is a synthetic gonadotropin-releasing hormone (GnRH) agonist peptide, widely used in reproductive medicine, oncology research, and veterinary clinical applications. It exhibits high binding affinity to GnRH receptors in the pituitary gland, effectively regulating follicle-stimulating hormone (FSH) and luteinizing hormone (LH) secretion.
- Product Name: Buserelin Acetate
- CAS Number: 57982-77-1
- Molecular Formula: C60H86N16O13
- Molecular Weight:≈ 1238.44 g/mol
- Sequence: Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt
- Appearance: White to off-white lyophilized powder
- Purity: ≥98.0% (HPLC)
- Form: Lyophilized powder
- Soluble in water, buffer solutions, and dilute acetic acid
- Recommended storage: -20°C, desiccated, protected from light
- Avoid repeated freeze-thaw cycles to maintain stability
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Reproductive Endocrinology Research
- Induces ovulation in assisted reproductive technology (ART) studies
- Regulates ovarian and testicular function in animal models
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Hormone-Dependent Tumor Research
- Used in preclinical studies for prostate cancer, breast cancer, and ovarian cancer
- Suppresses gonadal hormone production via pituitary desensitization
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Veterinary
- Applied in estrus synchronization and reproductive control in livestock
- Supports breeding management research
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Biomedical Assays
- Positive control for GnRH receptor binding assays
- Standard for in vitro and in vivo hormone regulation studies
Quality Control
- Tested by HPLC for purity
- Verified by Mass Spectrometry (MS) for identity
- Supplied with COA (Certificate of Analysis) and SDS
- Produced in GMP-compliant conditions for research and development use
