Specifications
Payment Terms :
T/T
Packagingmaterial :
PVC bottle or aluminium foil bag
Brand Name :
Bovita
Supply Ability :
10kg/month
Shelflife :
2 years
Cas :
89213-87-6
Sample :
Availiable
Storagecondition :
Store in a cool, dry place
Certification :
ISO/GMP
Usagedose :
Depends on specific application and peptide
MOQ :
5g
Packaging Details :
aluminium foil bag/Drum
Color :
white powder
Delivery :
100% safe delivery
Price :
100USD/G
Place of Origin :
Sichuan
Description

Carperitide (CAS 89213-87-6)


Chemical Name: Atrial Natriuretic Peptide (ANP) (1-28), human; α-hANP

Synonyms: Carperitide; ANP (1-28) human; Atrial Natriuretic Factor (1-28); HANF

CAS No.: 89213-87-6

Molecular Formula: C₁₂₇H₂₀₃N₄₅O₃₉S₃

Molecular Weight: 3080.44

Amino Acid Sequence:

H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH

(Disulfide bridge: Cys⁷–Cys²³)

Physical & Chemical Properties


  • Appearance: White to off-white lyophilized powder
  • Purity (HPLC): ≥98.0%
  • Single Impurity: ≤1.0%
  • Peptide Content: ≥80.0%
  • Acetate Content: 5.0–12.0% (acetate salt)
  • Water Content: ≤10.0%
  • Density: 1.55±0.1 g/cm³ (predicted)
  • Storage: -20°C, sealed, protect from light and moisture; lyophilized
  • Solubility: Soluble in water (clear, colorless solution)
  • Stability: Stable under recommended storage; avoid repeated freeze-thaw cycles

Description

Carperitide is a 28‑amino‑acid peptide hormone identical to human α‑atrial natriuretic peptide (α‑hANP), produced by recombinant or solid‑phase synthesis. It is a key endogenous regulator of cardiovascular homeostasis and fluid‑electrolyte balance, secreted by atrial myocytes in response to stretch/volume overload.
Mechanism of action:
  • Binds to NPR‑A receptors on vascular smooth muscle and renal cells → activates guanylyl cyclase → raises cGMP → vasodilation (reduces afterload) and natriuresis/diuresis (reduces preload)
  • Inhibits RAAS: suppresses renin, angiotensin II, aldosterone
  • Inhibits endothelin‑1 secretion → further vasodilation
  • Reduces sympathetic tone → lowers heart rate and blood pressure

Key Applications

  1. Cardiovascular Research: Heart failure, hypertension, vasodilation, natriuresis, cGMP signaling
  2. Pharmacology: Tool for studying NPR‑A, RAAS, and endothelin pathways; development for acute heart failure
  3. Clinical (Research Use Only): Acute decompensated heart failure (reduces preload/afterload, relieves symptoms)
  4. Biochemical Studies: Fluid balance, renal physiology, cardiac endocrinology


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GMP factory High purity peptide raw material carperitide peptide cas 89213-87-6

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Payment Terms :
T/T
Packagingmaterial :
PVC bottle or aluminium foil bag
Brand Name :
Bovita
Supply Ability :
10kg/month
Shelflife :
2 years
Cas :
89213-87-6
Contact Supplier
GMP factory High purity peptide raw material  carperitide  peptide cas 89213-87-6
GMP factory High purity peptide raw material  carperitide  peptide cas 89213-87-6
GMP factory High purity peptide raw material  carperitide  peptide cas 89213-87-6

Beijing Bovita Biomed Co.,Ltd.

Verified Supplier
1 Years
beijing, beijing
Since 2016
Business Type :
Manufacturer, Distributor/Wholesaler, Exporter
Total Annual :
5000000-6000000
Employee Number :
50~100
Certification Level :
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