EDTA & COMPLETE BLOOD COUNT Complete Blood Count Automatic Piping Blood Test Tube for Accurate Diagnosis

Key Characteristics

1. Anticoagulation Mechanism:
   EDTA (Ethylenediaminetetraacetic acid) chelates calcium ions (Ca²⁺) in blood, effectively blocking the coagulation cascade. It minimally alters blood cell morphology, preserving the original shape and volume of erythrocytes, leukocytes, and platelets159.

2. Platelet Protection:
   Significantly inhibits platelet aggregation, preventing pseudothrombocytopenia (PTCP) and ensuring accurate platelet counts3410.

3. Technical Design:

   • Uniform Coating: EDTA-K₂ or EDTA-K₃ is spray-coated evenly onto tube walls, enabling rapid dissolution and homogeneous mixing with blood28.

   • Vacuum System: Pre-set negative pressure ensures precise blood volume collection (e.g., 2ml/3ml/4ml tubes)410.

4. Compatibility:
   Compatible with automated hematology analyzers for high-throughput clinical testing310.

Primary Applications

1. Routine Hematology Tests:

   • Complete Blood Count (CBC), hemoglobin (Hb), white blood cell differential counts17.

   • Glycated hemoglobin (HbA1c) testing (diabetes diagnosis and monitoring)110.

2. Immunology & Molecular Biology:

   • Blood typing (ABO/Rh), cross-matching (pre-transfusion screening)24.

   • Pathogen detection (e.g., PCR analysis for malaria parasites or bacterial DNA)39.

3. Specialized Assays:

   • Cyclosporine level monitoring (post-transplant drug management), red cell folate quantification410.

   • Blood smear preparation (morphological evaluation under microscopy)18.

Operational Guidelines

• Mixing Protocol: Gently invert tubes 8–10 times (180°) immediately after collection to prevent clot formation; avoid vigorous shaking to reduce hemolysis risk45.

• Contraindications:
  Unsuitable for coagulation tests (e.g., PT/APTT) or calcium/potassium measurements (due to EDTA chelation interference)59.

• Time Sensitivity: Samples should be analyzed within 4–6 hours post-collection to maintain cell integrity

• EDTA blood collection tubes have become the gold standard tool in hematological testing due to their exceptional anticoagulation stability and cell morphology preservation capabilities. They are particularly essential for complete blood count (CBC), glycated hemoglobin (HbA1c) testing, and molecular diagnostics. The purple cap serves as a universal color code globally, and strict adherence to mixing protocols during operation is critical to ensure result reliability.