yellow Cap GEL&Clot Vacuum Blood Collection Tube high-throughput testing

Introduction to Serum Separator Tubes with Clot Activator

Serum separator tubes with clot activator (commonly known as "yellow-top tubes") are vacuum blood collection tubes designed for rapid serum preparation. Pre-filled with inert separator gel and high-activity clot activator, these tubes accelerate clotting post-collection. During centrifugation, the gel forms a stable barrier to completely separate serum from blood cells, ensuring sample purity and stability.

Application Scenarios

1. Biochemical Testing: Liver/kidney function, lipids, glucose, and other routine biochemistry.

2. Immunoassays: Hormones, tumor markers, infectious disease antibodies (e.g., HBV, HIV).

3. Therapeutic Drug Monitoring: Blood drug concentration analysis (e.g., cyclosporine, valproic acid).

4. Blood Bank Applications: Serum preparation for cross-matching.

5. Automated Platforms: Compatible with high-throughput laboratory automation systems.

Product Highlights

Usage Precautions

1. Collection Protocol:

   • Gently invert tube 5–8 times immediately after draw to mix clot activator with blood.

   • Avoid vigorous shaking to prevent hemolysis or gel barrier damage.

2. Centrifugation:

   • Centrifuge after complete clotting (1500–2000 ×g, 10–15 min) at 18–25°C.

   • Low-temperature centrifugation may impair gel solidification.

3. Sample Handling:

   • Transfer serum within 2 hours post-centrifugation to avoid prolonged gel contact.

   • For insufficient serum (e.g., lipemic samples), perform secondary centrifugation without disrupting the gel barrier.

Troubleshooting Guide

Basic Parameters

Key Value Proposition

These tubes integrate clot activation and gel separation technologies to enhance serum preparation efficiency and quality, reduce manual processing time, and minimize testing errors caused by improper sample handling. They are essential tools for standardized, high-throughput testing in modern laboratories.