Specifications
Model Number :
81-25-4
CAS :
81-25-4
Place of Origin :
China
Assay (HPLC) :
≥98.0%
Supply Ability :
1000kg
Residue on Ignition :
≤0.1%
Payment Terms :
T/T
Heavy Metals :
≤10 ppm
Delivery Time :
3-5days
Particle Size :
200 mesh pass rate ≥95%
Price :
180-200USD
Packaging Details :
Drum
Loss on Drying :
≤1.0%
Brand Name :
Xuanming
Product name :
Cholic Acid
MOQ :
1kg
Melting Point :
197–202 °C
Description
Cholic Acid Stable Solubility Bile Acid Compound Biochemical Protein Stabilization
Product Overview

Cholic Acid (CAS 81-25-4) is a primary trihydroxy bile acid compound widely used in biochemical research, bile acid signaling study, membrane protein extraction, and pharmaceutical intermediate development. It delivers mild solubilization to maintain native protein conformation and enzymatic activity, supporting consistent experimental results and scalable synthesis.

Product Properties
  • Chemical Name: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid
  • CAS Number: 81-25-4
  • Molecular Formula: C24H40O5
  • Molecular Weight: 408.58 g/mol
  • Appearance: White to off-white crystalline powder
  • Solubility: Slightly soluble in water; soluble in ethanol, methanol, glacial acetic acid
  • Stability: Stable under normal storage conditions; avoid strong light and high temperature
  • Key Function: Mild non-denaturing detergent; FXR nuclear receptor ligand; bile acid pathway regulator
Technical Parameters (8 Items)
Parameter Specification
Assay (HPLC) ≥98.0%
Melting Point 197–202 °C
Specific Rotation [α]D20 +34° to +40° (c=1, EtOH)
Loss on Drying ≤1.0%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Particle Size 200 mesh pass rate ≥95%
Storage Condition 2–8 °C, dry & sealed
Applications
  1. Biochemical Research: Used as mild detergent for membrane protein extraction and functional reconstitution.
  2. Pharmaceutical Intermediate: Key raw material for bile acid derivative synthesis and impurity reference preparation.
  3. Life Science Study: Applied in bile acid metabolism, FXR signaling pathway, and lipid regulation research.
  4. Reference Standard: Used as analytical reference for quality control in bile acid related drugs and reagents.
Quality Control
  • Produced under strict process control with full traceability.
  • Tested by HPLC, melting point, loss on drying, heavy metals and other indicators.
  • COA, MSDS, TDS documents available for download.
Packaging & Storage
  • Packaging: 1g, 5g, 25g, 100g, 500g, 1kg sealed bottles; custom bulk packaging supported.
  • Storage: Keep in cool, dry, sealed environment; avoid direct sunlight and high temperature.
  • Transportation: Non-hazardous for normal transportation; comply with international chemical logistics standards.

    Cholic Acid  Stable Solubility Bile Acid Compound Biochemical Protein Stabilization

    Cholic Acid  Stable Solubility Bile Acid Compound Biochemical Protein Stabilization

    Cholic Acid  Stable Solubility Bile Acid Compound Biochemical Protein Stabilization

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Cholic Acid Stable Solubility Bile Acid Compound Biochemical Protein Stabilization

Ask Latest Price
Model Number :
81-25-4
CAS :
81-25-4
Place of Origin :
China
Assay (HPLC) :
≥98.0%
Supply Ability :
1000kg
Residue on Ignition :
≤0.1%
Contact Supplier
Cholic Acid  Stable Solubility Bile Acid Compound Biochemical Protein Stabilization
Cholic Acid  Stable Solubility Bile Acid Compound Biochemical Protein Stabilization

Changzhou Xuanming Chemical Industry Co., Ltd

Verified Supplier
1 Years
jiangsu, changzhou
Business Type :
Manufacturer
Main Products :
Total Annual :
20000000-30000000
Employee Number :
>10
Certification Level :
Verified Supplier
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