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Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study
Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study
Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study
Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study
Specifications
Model Number :
CAS 101469-92-5
Molecular Formula :
C₉H₁₇NO₃
Payment Terms :
T/T
Storage Feature :
Sensitive to humid air
Delivery Time :
5-7 work days
Place of Origin :
China
Molecular Weight :
187.24
Supply Ability :
1T
Price :
353 – 412USD
Packaging Details :
drum
Optical Purity :
≥99% ee
Brand Name :
Xuanming
CAS Number :
101469-92-5
MOQ :
1 kg
Appearance :
Colorless transparent viscous liquid
Description
(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate
Product Overview

(S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate is a chiral five-member nitrogen heterocyclic ester compound. It holds fixed single stereoconfiguration and mild reaction activity, with steady crystal form and low impurity content. The product is widely adopted in chiral fragment construction, asymmetric synthesis and custom fine chemical research.

Technical Parameter Table (8 items)
Test Index Standard Value
Full Chemical Name (S)-tert-Butyl 3-hydroxypyrrolidine-1-carboxylate
Molecular Formula C₉H₁₇NO₃
Molecular Weight 187.24
Appearance Colorless transparent viscous liquid
Optical Purity ≥99% ee
Refractive Index 1.462~1.468 (25℃)
Usable Purity 98%, 99%
Storage Feature Sensitive to humid air
Core Product Properties
1. Stable Single Chiral Configuration

The pyrrolidine ring maintains fixed S stereostructure under normal processing temperature, no racemization during common synthetic reactions to guarantee consistent optical performance.

2. Moderate Hydroxyl Activity

The terminal hydroxyl group can carry out esterification and etherification under mild conditions, serving as accessible active site for deriving complex heterocyclic molecules.

3. Good Solvent Compatibility

Mixes uniformly with common polar organic solvents; immiscible with water and alkane medium, matching general organic synthesis process systems.

4. Low Racemization Risk

Tert-butyl carbamate protecting group effectively locks ring stereoconformation, resisting structural inversion under conventional heating below 105℃.

5. Uniform Batch Character

Continuous purification process stabilizes optical purity and composition across batches, lowering deviation of lab synthesis test data.

6. Mild Thermal Stability

Complete molecular structure keeps intact below 105℃; long heating above 180℃ triggers partial deprotection decomposition.

7. Moisture Sensitivity

Contact with excessive water vapor slowly reduces optical purity, requiring airtight sealed packaging during preservation and transportation.

8. Protective Group Convenience

Tert-butoxycarbonyl group can be removed under weak acidic conditions, offering flexible routes for subsequent molecular modification.

Application Scope
  1. Chiral building unit for five-member nitrogen heterocycle derivation
  2. Raw material for asymmetric organic synthesis and stereochemistry laboratory exploration
  3. Precursor for constructing multi-substituted pyrrolidine structural fragments
  4. Custom fine chemical intermediate for chiral material preparation
Storage & Handling Guidance

Seal inside airtight containers and store under constant low temperature dry environment. Isolate from humid air, strong acid and high temperature sources. Shorten packaging opening time to reduce moisture contact.

Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study

Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study

Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study

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Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study

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Product Detail
Model Number :
CAS 101469-92-5
Molecular Formula :
C₉H₁₇NO₃
Payment Terms :
T/T
Storage Feature :
Sensitive to humid air
Delivery Time :
5-7 work days
Place of Origin :
China
Contact Supplier
Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study
Chiral Moisture-resistant Pyrrolidine Ester Intermediate for Organic Material Study

Changzhou Xuanming Chemical Industry Co., Ltd

Verified Supplier
1 Years
jiangsu, changzhou
Business Type :
Manufacturer
Main Products :
API, Custom Peptide, Custom Chemicals
Total Annual :
20000000-30000000
Employee Number :
>10
Certification Level :
Verified Supplier
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