GMP Negative Pressure Weighing Booth HEPA Filtration | Dust Containment System
Engineered for precise material handling in pharmaceutical production, this weighing booth prevents cross-contamination while maintaining GMP-compliant environmental conditions. Ideal for potent compound weighing and dispensing operations.
Technical Specifications
| Parameter Name |
Value |
| Main Enclosure Material |
SUS304 stainless steel, 1.2mm thickness |
| Control Interface |
7-inch touchscreen with real-time monitoring |
| Inverter System |
1.5KW/unit (Oray brand) |
| Pressure Monitoring |
3 differential pressure gauges (local & remote) |
| Airflow Sensors |
Integrated wind speed sensors with remote output |
| Electrical Outlets |
2× industrial sockets (Chint brand) |
| Fan Configuration |
DSX-240 (1.5KW)×2 units with flow equalization membrane |
| Work Surface Dimensions |
700W×500D×800H mm (weighing table) |
| Internal Dimensions |
1500W×1400D×2000H mm |
| External Dimensions |
1600W×2000D×2670H mm |
| Environmental Control |
18-26°C, 45-65% RH (GMP Grade D) |
Optional Dimensions
| Model |
Work Surface (W×D×H, mm) |
Internal Dimensions (W×D×H, mm) |
External Dimensions (W×D×H, mm) |
| Model 1 |
700 × 500 × 800 |
2100 × 1000 × 2000 |
2200 × 1600 × 2670 |
| Model 2 |
700 × 500 × 800 |
2900 × 1400 × 2000 |
3000 × 2000 × 2670 |
| Model 3 |
700 × 500 × 800 |
3750 × 1400 × 2000 |
3850 × 2000 × 2670 |
| Model 4 |
700 × 500 × 800 |
4400 × 1400 × 2000 |
4500 × 2000 × 2670 |
Product Features
Advanced Containment Technology
- Negative pressure design: Maintains -15Pa to -30Pa gradient to prevent dust escape
Precision Process Control
- Dual 1.5KW fans: Ensure stable airflow (0.45±0.1m/s) during material transfers
- Real-time monitoring: Touchscreen displays differential pressure, wind speed, and filter status
GMP-Compliant Construction
- 304 stainless steel: Resists disinfectants and prevents particle shedding
- Seamless welds: Eliminate contamination traps per EU GMP Annex 1
Operational Safety
- Automatic alarms: Trigger for pressure deviations or filter saturation
- Emergency stop: Instantly halts operations if containment is compromised
Application Scenarios
- API Weighing: Maintains ISO 8 conditions for active pharmaceutical ingredient measurement
- Excipient Preparation: Prevents cross-contamination in multi-product facilities
- Sterile Formulation: Protects sterile cores during tablet compression line feeding
- R&D Laboratories: Enables safe handling of experimental compounds in early development
Technical Validation
- Filter Efficiency: EN 1822-5:2009 tested at MPPS
- Pressure Control: Validated per ISO 14644-3 Annex B4
- Material Compliance: ASTM A240 304 stainless steel
Frequently Asked Questions
Q1: How does the negative pressure system prevent hazardous powder exposure?
The booth maintains -15Pa to -30Pa pressure gradient with dual 1.5KW fans, creating inward airflow that contains particles. This exceeds OSHA 29 CFR 1910.134 requirements for hazardous handling.
Q2: What makes your filter more effective than standard HEPA?
Our MRJH filters are MPPS-tested, capturing particles - critical for potent compounds like cytotoxics. Includes DOP test ports for routine validation.
Q3: Can the system handle continuous weighing of multiple APIs?
Yes, the 304 stainless steel interior and flow equalization membrane prevent cross-contamination during product changeovers. Touchscreen logs each session for 21 CFR Part 11 compliance.