1,1,3,3-Tetramethylguanidine As A Nonaqueous Solvent Cas 80-70-6
DESCRIPTION
Tetramethylguanidine is a colorless, odorless, crystalline solid that is soluble in water and most organic solvents.
Tetramethylguanidine is an organic compound with the formula HNC(N(CH3)2)2. This colourless liquid is a strong base, as judged by the high pKa of it conjugate acid.It was originally prepared from tetramethylthiourea via S-methylation and amination, but alternative methods start from cyanogen iodide.
Specification
CAS No. | 80-70-6 |
MF | C5H13N3 |
EINECS No. | 201-302-7 |
Place of Origin | China |
Density | 0.9g/cm3 |
Water solubility | miscible |
Refractive index | 1.445 |
Flash point | 60°C |
Vapour Pressure | 2.09mmHg at 25°C |
Appearance | Liquid |
Mp | -30℃ |
Bp | 163.2°C at 760 mmHg |
Molecular Weight | 115.1768 |
Sample | Availiable |
Safety Description | S16:; S26:; S36/37/39:; S45:; |
Risk Codes | R10:; R20/22:; R34:; |
Product application
In organic synthesis, 1,1,3,3-tetramethylguanidine is used as a strong, non nucleophilic base. 1,1,3,3-tetramethylguanidine is an efficient and selective catalyst for alcohol benzoylation. Widely used in the synthesis of pharmaceutical and chemical raw materials. It is mainly used in the production of cephalosporins in medicine. It is used as a catalyst for polyurethane foam, as well as for uniform dyeing of nylon, wool and other proteins