1,1,3,3-Tetramethylguanidine As A Nonaqueous Solvent Cas 80-70-6
DESCRIPTION
Tetramethylguanidine is a colorless, odorless, crystalline solid that is soluble in water and most organic solvents.
Tetramethylguanidine, abbreviated as TMG, is a strong organic base catalyst with wide industrial applications, mainly used as a cosolvent for the synthesis of new antibiotic cephalosporins; It can also be used as a catalyst for polyurethane foam; It can also be used for dyeing nylon, wool, and other proteins to improve their durability.
Specification
CAS No. | 80-70-6 |
MF | C5H13N3 |
EINECS No. | 201-302-7 |
Place of Origin | China |
Density | 0.9g/cm3 |
Water solubility | miscible |
Refractive index | 1.445 |
Flash point | 60°C |
Vapour Pressure | 2.09mmHg at 25°C |
Appearance | Liquid |
Mp | -30℃ |
Bp | 163.2°C at 760 mmHg |
Molecular Weight | 115.1768 |
Sample | Availiable |
Safety Description | S16:; S26:; S36/37/39:; S45:; |
Risk Codes | R10:; R20/22:; R34:; |
Product application
In organic synthesis, 1,1,3,3-tetramethylguanidine is used as a strong, non nucleophilic base. 1,1,3,3-tetramethylguanidine is an efficient and selective catalyst for alcohol benzoylation. Widely used in the synthesis of pharmaceutical and chemical raw materials. It is mainly used in the production of cephalosporins in medicine.Tetramethylguanidine is mainly used as a strong, non-nucleophilic base for alkylations, often as a substitute for the more expensive DBU and DBN. Since it is highly water-soluble, it is easily removed from mixtures in organic solvents. It is also used as a base-catalyst in the production of polyurethane.