Chitosan Oligosaccharide for Bone & Joint Health | Full English Product Description

1. Physicochemical Properties

• Molecular weight: Low molecular weight, average molecular weight ≤ 3000 Da, degree of polymerization DP 2–10
• Solubility: Fully water-soluble at room temperature, no turbidity or precipitation; superior solubility compared with macromolecular chitosan
• Absorption: High intestinal bioavailability, rapid absorption after oral administration
• Deacetylation Degree (DD): 75% – 95%, stable molecular structure
• Appearance & Odor: White to off-white fine powder, odorless, slightly sweet taste
• Quality Index: Low heavy metal content, non-GMO, no artificial additives, low viscosity, good fluidity, easy to formulate into capsules, powder, tablets and oral liquids for joint care.

2. Mechanisms & Efficacy Data for Bone & Joint Protection

2.1 Regulate Joint Immunity & Relieve Joint Inflammation

• COS acts on macrophages and immune receptors, significantly down-regulates pro-inflammatory factors in joint tissues. Test data shows it reduces IL-1β by 41%, TNF-α by 37% and IL-6 by 34% in inflammatory joint models.
• It inhibits the over-activation of NF-κB signaling pathway, effectively alleviating joint redness, swelling and inflammatory pain.
• Optimizes systemic immune balance, reduces recurrent joint discomfort caused by low immunity.

2.2 Protect & Repair Articular Cartilage

• Inhibits the activity of matrix metalloproteinases (MMPs) that decompose cartilage matrix, reducing MMP-3 expression by 39%, so as to prevent cartilage extracellular matrix loss.
• Promotes the proliferation and activity of chondrocytes, improves the self-repair ability of damaged cartilage tissue.
• Maintains the integrity of cartilage surface, delays joint degenerative changes.

2.3 Lubricate Joints & Improve Mobility

• Promotes the secretion of synovial fluid inside joints, increases joint lubrication, reduces friction between bones.
• Alleviates joint stiffness caused by dry synovial fluid; clinical observation shows it improves joint flexibility and range of motion obviously after continuous use.

2.4 Support Bone Health & Strengthen Bone Tissue

• Regulates calcium metabolism in the body, helps improve calcium absorption and deposition, maintains normal bone density.
• Synergistically protects bone and joint system, suitable for people with weak bones and age-related joint decline.

3. Summary

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