Prolactin is a polypeptide hormone, also known as prolactin (PRL), which is one of the hormones secreted by pituitary gland. It can promote the hyperplasia of mammary gland, the production and excretion of milk, and also participate in various functions of the body, especially the regulation of reproductive function. The determination of PRL concentration is helpful to the diagnosis of hypothalamic pituitary dysfunction. Pituitary tumor can cause hyperprolactinemia, sometimes also related to male impotence. High PRL level is generally related to galactorrhea and amenorrhea. After drug treatment, the menstruation can return to normal after the decline of PRL.
Detection range | sample size | Sample type | Test time |
20~4000μIU/mL | 20μl | Serum / plasma / whole blood | 15min |
PRL | pathogeny |
↑ | Premature ovarian failure, hypothyroidism, precocious puberty, pituitary or hypothalamic tumors, hyperprolactinemia amenorrhea, renal failure, luteal dysfunction, long-term breast-feeding, male and female breasts, neuropsychiatric stimulation, drug effects |
↓ | Hypopituitarism, Sheehan's syndrome, uterine functional bleeding, simple prolactin deficiency syndrome, taking anti PRL drugs |
Department of Gynecology, obstetrics, oncology, reproductive medicine and genetics
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